Prof. Dr. med. dent. Florian Just Wegehaupt
Head Division of Preventive Dentistry and Oral Epidemiology
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Research Interests
Tooth wear is mainly caused by caries and erosion. Erosions are defined as acid induced tooth wear without involvement of bacteria. Central to these processes is the dissolution of hydroxyapatite minerals of the teeth. Aim of our research is to understand the basic processes causing these kinds of tooth wear. Furthermore, we are investigating and developing new preventive approaches to prevent these acid induced tooth damages. These preventive approaches are focusing on the tooth wear causing acids and the dental hard tissues itself.
Selected publications
Wegehaupt FJ, Buchalla W, Sener B, Attin T, Schmidlin PR. (2013)
Cerium
Chloride Reduces Enamel Lesion Initiation and Progression in vitro.
Caries Res. 2013;48(1):45-50
Wegehaupt FJ, Tauböck TT, Sener B, Attin T. (2012)
Long-term
protective effect of surface sealants against erosive wear by intrinsic and
extrinsic acids.
J Dent. 2012 May;40(5):416-22
Wegehaupt FJ, Sener B, Attin T, Schmidlin PR. (2011)
Anti-erosive
potential of amine fluoride, cerium chloride and laser irradiation application
on dentine.
Arch Oral Biol. 2011;56(12):1541-7
Wegehaupt F, Günthart N, Sener B, Attin T. (2011)
Prevention
of erosive/abrasive enamel wear due to orange juice modified with dietary
supplements.
Oral Dis. 2011;17(5):508-14
Wegehaupt FJ, Attin T. (2010)
The
role of fluoride and casein phosphopeptide/amorphous calcium phosphate in the
prevention of erosive/abrasive wear in an in vitro model using hydrochloric
acid.
Caries Res. 2010;44(4):358-63
Wegehaupt FJ, Solt B, Sener B, Wiegand A, Schmidlin PR, Attin T. (2009)
Influence
of fluoride concentration and ethanol pre-treatment on the reduction of the
acid susceptibility of enamel.
Arch Oral Biol. 2009 Sep;54(9):823-9
Links
Publications in ZORA (Zurich Open Repository and Archive)
ZORA Publication List
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Publications
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Methods for Assessment of Dental Erosion and Erosive Tooth Wear in Different Research Settings. In: Schlueter, Nadine; Ganss, Carolina; Lussi, Adrian. Erosive Tooth Wear : From Diagnosis to Therapy (3rd, revised and updated edition). Basel: Karger, 81-103.
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Cleaning Efficacy of Toothpastes With Varying Abrasiveness-An In Vitro Investigation on Bovine Dentin. International Journal of Dental Hygiene, 23(2):256-266.
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The Influence of Interdental Brushes and Toothpaste On Approximal Enamel and Dentine Abrasion - A Laboratory Study. Oral Health & Preventive Dentistry, 23:217-224.
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Influence of the relative enamel abrasivity of toothpastes (REA value) on the wear of eroded enamel. Swiss Dental Journal, 135(2):27-36.
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Interplay Between the In-Vitro Cleaning Performance and Wear of Manual Toothbrushes in Fixed Orthodontic Appliances. Oral Health & Preventive Dentistry, 22:681-688.
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In-Vitro Tooth Cleaning Efficacy and Filament End Rounding of Different Manual Children's Toothbrushes. Oral Health & Preventive Dentistry, 22:277-284.
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Cleaning performance of electric toothbrushes around brackets applying different brushing forces: an in-vitro study. Scientific Reports, 14(1):5921.
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Supplementation of Energy Drinks with Green Tea Extract: Effect on In Vitro Abrasive/Erosive Dentin Wear. Oral Health & Preventive Dentistry, 21(1):391-396.
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Dentin Loss and Surface Alteration Through Chemical and Chemomechanical Challenge after Initial Root Instrumentation. Oral Health & Preventive Dentistry, 21(1):171-178.
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Effect of Toothbrush Bristle Stiffness and Brushing Force on Cleaning Efficacy. Oral Health & Preventive Dentistry, 21(1):153-162.
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Abrasive Enamel and Dentin Wear Resulting from Brushing with Toothpastes with Highly Discrepant Relative Enamel Abrasivity (REA) and Relative Dentin Abrasivity (RDA) Values. Oral Health & Preventive Dentistry, 21(1):41-48.
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Relative dentin and enamel abrasivity of charcoal toothpastes. International Journal of Dental Hygiene, 21(1):149-156.
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Effect of brushing force on the abrasive dentin wear using slurries with different abrasivity values. International Journal of Dental Hygiene, 21(1):172-177.
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In vitro evaluation of fissure sealants’ wear under erosive, abrasive and erosive/abrasive conditions. European Archives of Paediatric Dentistry, 24(1):55-61.
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Salivary Flow Rate During Toothbrushing. Oral Health & Preventive Dentistry, 20(1):465-474.
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Interplay Between the In-Vitro Cleaning Performance and Wear of Manual Toothbrushes. Oral Health & Preventive Dentistry, 20(1):457-464.
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Effect of tapered-end and round-end bristles on the abrasive dentine wear applying increasing brushing forces. Acta Odontologica Scandinavica, 80(6):465-469.
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Diamond particles in toothpastes: in-vitro effect on the abrasive enamel wear. BMC Oral Health, 22(1):248.
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Influence of pretreatments on microtensile bond strength to eroded dentin using a universal adhesive in self-etch mode. International Journal of Adhesion and Adhesives, 114:103108.
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Effect of the toothbrush tuft arrangement and bristle stiffness on the abrasive dentin wear. Scientific Reports, 12(1):840.
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Wear of conventional and pre-polymerized composite materials under erosive/abrasive conditions. Swiss Dental Journal, 132(2):106-112.
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Adhesive application before hydrofluoric acid etching during repair procedure in dentistry?. International Journal of Adhesion and Adhesives, 111:102960.
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Effect of a sonic toothbrush on the abrasive dentine wear using toothpastes with different abrasivity values. International Journal of Dental Hygiene, 19(4):407-412.
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Effect of toothbrush bristle stiffness and toothbrushing force on the abrasive dentine wear. International Journal of Dental Hygiene, 19(4):355-359.
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Effect of dentin pretreatment on the resulting abrasive dentin wear. BMC Oral Health, 21:295.
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Cariogenic potential of oral nutritional supplements measured by intraoral plaque pH telemetry. Clinical Nutrition, 40(5):3448-3453.
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Salivary Biomarkers for Dental Caries Detection and Personalized Monitoring. Journal of Personalized Medicine, 11(3):235.
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Toothpastes with Enzymes Support Gum Health and Reduce Plaque Formation. International Journal of Environmental Research and Public Health, 18:835.
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Einschätzung von Zahnärzten zu vermuteten Gründen für das Scheitern von Kompositfüllungen mittels Adhäsivtechnik. Swiss Dental Journal, 131(1):45-52.
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Green Tea Extract Reduces the Erosive Dentine Wear Caused by Energy Drinks In Vitro. Oral Health & Preventive Dentistry, 19(1):573-578.
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Enamel Softening Can Be Reduced by Rinsing with a Fluoride Mouthwash Before Dental Erosion but Not with a Calcium Solution. Oral Health & Preventive Dentistry, 19(1):587-594.
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Homemade Modification of Salad Dressings to Reduce Their Erosive Potential. Oral Health & Preventive Dentistry, 19(1):433-440.
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Erosive Potential of Bottled Salad Dressings. Oral Health & Preventive Dentistry, 19(1):51-57.
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Erosiver Zahnhartsubstanzverlust bei Sportlern. Quintessenz Zahnmedizin, 72(9):1008-1017.
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Buffer Solution Reduces Acidic Toothpaste Abrasivity Measured in Standardized Tests. Frontiers in Dental Medicine, 1:612298.
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Microbial Analysis of Saliva to Identify Oral Diseases Using a Point-of-Care Compatible qPCR Assay. Journal of Clinical Medicine, 9(9):2945.
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RDA and REA Values of Commercially Available Toothpastes Utilising Diamond Powder and Traditional Abrasives. Oral Health & Preventive Dentistry, 18(1):807-814.
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Dentin Abrasivity and Cleaning Efficacy of Novel/Alternative Toothpastes. Oral Health & Preventive Dentistry, 18(1):713-718.
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Mechanical properties of toothpastes with diamond abrasives. Journal of Esthetic and Restorative Dentistry, 32(4):416-423.
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Erosive loss of tooth substance is dependent on enamel surface structure and presence of pellicle - An in vitro study. Archives of Oral Biology, 112:104686.
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Erosive/Abrasive Enamel Wear While Using a Combination of Anti-Erosive Toothbrush/-Paste. Oral Health & Preventive Dentistry, 18(1):53-59.
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Prevention of Enamel Softening by Rinsing with a Calcium Solution before Dental Erosion. Caries Research, 54(2):127-133.
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Pure hydroxyapatite as a substitute for enamel in erosion experiments. Journal of Dentistry, 84:89-94.