Prof. Dr. med. dent. Daniel S. Thoma
Oberarzt
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Clinical Specialisations
Implantology, Reconstructive Dentistry, Esthetic Dentistry
Research Interests
- preclinical and clinical research
- hard tissue regeneration with and without biologic mediators
- soft tissue regeneration with and without biologic mediators
- implant dentistry
- fixed reconstructive dentistry
Selected publications
Thoma DS, Villar D, Cochran DL, Hämmerle CHF, Jung RE. Tissue integration of collagen-based matrices: an experimental study in mice. Clin Oral Implants Res, accepted
Impact Factor: 2.920
Thoma DS, Sancho-Puchades M, Ettlin D, Hämmerle CHF, Jung RE. Impact of a collagen matrix on early healing, esthetics and patient morbidity in oral mucosal wounds – a randomized study in humans. J Clin Periodontol 39: 157-165.
Impact factor: 3.933
Jung RE, Zembic A, Pjetursson B, Zwahlen M, Thoma DS. Systematic review of the survival rate and the incidence of biological, technical and esthetic complications of single crowns on implants reported in longitudinal studies of at least 5 years. Clin Oral Implants Res 2012 Oct; 23 Suppl 6:2-21
Impact Factor: 2.920
Thoma DS, Hämmerle CHF, Cochran DL, Jones AA, Görlach C, Uebersax L, Mathes S. Graft-Hausner U, Jung RE.. Soft tissue volume augmentation by the use of collagen-based matrices in the dog mandible - a histologic analysis Journal of Clinical Periodontology. 2011
Impact Factor: 3.933
Thoma DS, Benic GI, Zwahlen M, Hämmerle CHF, Jung RE. A systematic review assessing soft tissue augmentation techniques. Clin Oral Implants Res 2009;20 Suppl 4:146-165.
Impact Factor: 2.920
Thoma DS, Jung RE, Schneider D, Cochran DL, Ender A, Jones AA, Görlach C, Übersax L, Graf-Hausner U, Hämmerle CHF. Soft tissue augmentation by the use of collagen based matrices - a volumetric analysis. J Clin Periodontol 2010; 37:659-666
Impact Factor: 3.933
Links
Publications in ZORA (Zurich Open Repository and Archive)
ZORA Publication List
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Publications
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Bone Regeneration After Sinus Floor Elevation in an Intact Sinus or a Sinus With Prior Large Membrane Perforation: A Preclinical Study Using a Rabbit Sinus Model. Journal of Clinical Periodontology, 52(3):421-433.
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Rehabilitation of the Worn Dentition With Direct and Indirect Minimally Invasive Concepts-A Systematic Review and Meta-Analysis. Journal of Esthetic and Restorative Dentistry, 37(3):690-701.
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Preclinical Investigation on the Effect of Collagen Matrix With Polydeoxyribonucleotide at Buccally Positioned Implants. Clinical Implant Dentistry and Related Research, 27(1):e13411.
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Effects of Polydeoxyribonucleotide (PDRN) on Endosinus Bone Regeneration Following Sinus Floor Elevation: An Experimental In Vivo Pilot Study. Clinical Oral Implants Research, 36(2):239-249.
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Soft Tissue Contours at Pontic Sites With or Without Soft Tissue Grafting-A 15-Year Follow-Up of a Controlled Clinical Study. Journal of Esthetic and Restorative Dentistry, 37(2):352-360.
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Maintenance Costs, Time, and Efforts Following Implant Therapy With Fixed Restorations Over an Observation Period of 10 Years: A Randomized Controlled Clinical Trial. Clinical Implant Dentistry and Related Research, 27(1):e13405.
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The Apical Tooth Replantation with Surgical Intrusion Technique (ATR-SIT) for the Regenerative Treatment of Hopeless Teeth: A Report of Two Cases. International Journal of Periodontics and Restorative Dentistry, 45(1):59-69.
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A 7.5-year randomized controlled clinical study comparing cemented and screw-retained one-piece zirconia-based implant-supported single crowns. Clinical Oral Implants Research, 35(12):1669-1675.
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3D surface defect map for assessing buccolingual profile of single tooth gaps following alveolar ridge preservation. Clinical Implant Dentistry and Related Research, 26(6):1101-1110.
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Long-term clinical and radiographic outcomes of a bone-level, 2-piece, internal connection implant system with coronal microthreads over 10 years of follow-up: a retrospective clinical study. Journal of Periodontal & Implant Science, 54(6):e28.
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Does an untreated peri-implant dehiscence defect affect the progression of peri-implantitis?: A preclinical in vivo experimental study. Clinical Oral Implants Research, 35(11):1373-1381.
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Clinical, radiographic and patient-reported outcomes of zirconia and titanium implants in the posterior zone after 1 year of loading-A randomized controlled trial. Clinical Oral Implants Research, 35(11):1428-1439.
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Comparing Small Buccal Dehiscence Defects Treated with or without Guided Bone Regeneration. A Sub-Analysis of a RCT. International Journal of Periodontics and Restorative Dentistry:Epub ahead of print.
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Effects of hard- and/or soft-tissue grafting with early implant placement: Histomorphometric outcomes of an exploratory study in canines. Clinical Oral Implants Research, 35(10):1324-1334.
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Enhancing guided bone regeneration with cross-linked collagen-conjugated xenogeneic bone blocks and membrane fixation: A preclinical in vivo study. Clinical Oral Implants Research, 35(10):1226-1239.
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Clinical Outcomes of Single Implant Supported Crowns Utilising the Titanium Base Abutment : A 7.5-Year Prospective Cohort Study. Journal of Dentistry, 149:105306.
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Effects of implant placement timing and type of soft-tissue grafting on histological and histomorphometric outcomes in a preclinical canine model. Journal of Clinical Periodontology, 51(7):840-851.
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Clinical Outcomes of Tooth- and Implant- Supported Restorations Performed in a University-Based Undergraduate Program After 13 to 15 Years. International Journal of Prosthodontics, (3):261-270.
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Flapless early implant placement into the uncalcified provisional matrix-Does it lead to osseointegration of the implant? A preclinical study. Journal of Clinical Periodontology, 51(6):766-773.
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Impact of keratinized mucosa on implant-health related parameters: A 10-year prospective re-analysis study. Clinical Implant Dentistry and Related Research, 26(3):554-563.
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Augmentation of keratinized tissue using autogenous soft-tissue grafts and collagen-based soft-tissue substitutes at teeth and dental implants: Histological findings in a pilot pre-clinical study. Journal of Clinical Periodontology, 51(5):665-677.
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Randomized controlled multi-centre study comparing shorter dental implants (6 mm) to longer dental implants (11-15 mm) in combination with sinus floor elevation procedures: 10-year data. Journal of Clinical Periodontology, 51(4):499-509.
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Early implant placement in sites with ridge preservation or spontaneous healing: histologic, profilometric, and CBCT analyses of an exploratory RCT. Journal of Periodontal & Implant Science, 54(2):108-121.
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Ridge preservation using a self-retaining block type bone substitute for extraction sockets with buccal dehiscence defects - A preclinical study. Clinical Oral Implants Research, 35(3):330-339.
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Clinical and histological wound healing patterns of collagen-based substitutes: An experimental randomized controlled trial in standardized palatal defects in humans. Journal of Clinical Periodontology, 51(3):319-329.
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Stromal cells associated with soft tissue augmentation by a volume stable collagen matrix (VCMX) are predominated by anti-inflammatory/reparative macrophages. International Journal of Periodontics and Restorative Dentistry, 44(5):601-611.
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The 3D emergence profile on implant-supported restorations: A method for evaluating restorative angles. Journal of Esthetic and Restorative Dentistry, 35(8):1264-1270.
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Survival and complication rates of two dental implant systems supporting fixed restorations: 10-year data of a randomized controlled clinical study. Clinical Oral Investigations, 27(12):7327-7336.
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Randomized controlled pilot study comparing small buccal defects around dental implants treated with a subepithelial connective tissue graft or with guided bone regeneration. Clinical Oral Implants Research, 34(10):1094-1105.
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Zirkonoxidimplantate: Does size matter?. Implantologie:247-254.
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13-year follow-up of a randomized controlled study on zirconia and titanium abutments. Clinical Oral Implants Research, 34(9):911-919.
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Efficacy of a collagen matrix for soft tissue augmentation after implant placement compared to connective tissue grafts: A multicenter, noninferiority, randomized controlled trial. Clinical Oral Implants Research, 34(9):999-1013.
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Soft tissue contour changes at implant sites with or without soft tissue grafting in the esthetic zone: A retrospective case-control study with a 12-year follow-up. Clinical Oral Implants Research, 34(5):521-530.
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Outcome measures and methods of assessment of soft tissue augmentation interventions in the context of dental implant therapy: A systematic review of clinical studies published in the last 10 years. Journal of Clinical Periodontology, 50(S25):83-95.
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The peri-implant mucosa color: A systematic appraisal of methods for its assessment and clinical significance. Clinical Implant Dentistry and Related Research, 25(2):224-240.
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Minimal invasiveness in soft tissue augmentation at dental implants: A systematic review and meta-analysis of patient-reported outcome measures. Periodontology 2000, 91(1):182-198.
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Randomized controlled pilot study assessing efficacy, efficiency, and patient-reported outcomes measures of chairside and labside single-tooth restorations. Journal of Esthetic and Restorative Dentistry, 35(1):74-83.
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The L-shape technique in guided bone regeneration with simultaneous implant placement in the esthetic zone: A step-by-step protocol and a 2-14 year retrospective study. Journal of Esthetic and Restorative Dentistry, 35(1):197-205.
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Tissue integration and biodegradation of soft tissue substitutes with and without compression: an experimental study in the rat. Clinical Oral Investigations, 27(1):313-328.
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Radiographic density changes may be associated with overloading and implant loss on short implants: A 5-year analysis of a randomized controlled clinical trial. Clinical Implant Dentistry and Related Research, 24(6):766-775.
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Infra- and labio-position of two maxillary central incisor implants in an older adult at a 17-year follow-up. Gerodontology, 39(4):429-433.
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Anterior implant restorations with a convex emergence profile increase the frequency of recession: 12-month results of a randomized controlled clinical trial. Journal of Clinical Periodontology, 49(11):1145-1157.
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Pontic site development for fixed dental prostheses with and without soft tissue grafting: 1-year results of a cohort study. Clinical Oral Investigations, 26(10):6305-6316.
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Effect of collagen membrane fixation on ridge volume stability and new bone formation following guided bone regeneration. Journal of Clinical Periodontology, 49(7):684-693.
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Restorative angle of zirconia restorations cemented on non-original titanium bases influences the initial marginal bone loss: 5-year results of a prospective cohort study. Clinical Oral Implants Research, 33(7):745-756.
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Effect of peri-implant mucosal thickness on esthetic outcomes and the efficacy of soft tissue augmentation procedures: Consensus report of group 2 of the SEPA/DGI/OF workshop. Clinical Oral Implants Research, 33 Suppl(Suppl 23):100-108.
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The influence of thin as compared to thick peri-implant soft tissues on aesthetic outcomes: A systematic review and meta-analysis. Clinical Oral Implants Research, 33 Suppl(Suppl 23):56-71.
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Buccal soft tissue dehiscence defects at dental implants-associated factors and frequency of occurrence: A systematic review and meta-analysis. Clinical Oral Implants Research, 33 Suppl:109-124.
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Interproximal contact loss at implant sites: a retrospective clinical study with a 10-year follow-up. Clinical Oral Implants Research, 33(5):482-491.
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Five-year randomized controlled clinical study comparing cemented and screw-retained zirconia-based implant-supported single crowns. Clinical Oral Implants Research, 33(5):537-547.
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Dimensional ridge changes in conjunction with four implant timing protocols and two types of soft tissue grafts: A pilot pre-clinical study. Journal of Clinical Periodontology, 49(4):401-411.
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Effect of collagen membrane and of bone substitute on lateral bone augmentation with titanium mesh: An experimental in vivo study. Clinical Oral Implants Research, 33(4):413-423.
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Immediate implant placement in conjunction with guided bone regeneration and/or connective tissue grafts: an experimental study in canines. Journal of Periodontal & Implant Science, 52(2):170-180.
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On the discrepancy between professionally assessed and patient-reported outcome measures. Journal of Periodontal & Implant Science, 52(2):89-90.
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Cemented versus screw-retained zirconia-based single-implant restorations: 5-year results of a randomized controlled clinical trial. Clinical Oral Implants Research, 33(4):353-361.
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Informative title: Guided bone regeneration with and without rhBMP-2: 17-year results of a randomized controlled clinical trial. Clinical Oral Implants Research, 33(3):302-312.
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Randomized controlled clinical study comparing two types of two-piece dental implants supporting fixed restorations-Results at 8 years of loading. Clinical Oral Implants Research, 33(3):333-341.
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Management and prevention of soft tissue complications in implant dentistry. Periodontology 2000, 88(1):116-129.
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Membrane fixation enhances guided bone regeneration in standardized calvarial defects: A pre-clinical study. Journal of Clinical Periodontology, 49(2):177-187.
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Contour Changes Following Implant Placement and Concomitant Soft Tissue Augmentation Applying a Volume-Stable Collagen Matrix. International Journal of Periodontics and Restorative Dentistry, 42(4):515-522.
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Primary bone augmentation leads to equally stable marginal tissue conditions comparing the use of xenograft blocks infused with BMP-2 and autogenous bone blocks: A 3D analysis after 3 years. Clinical Oral Implants Research, 32(12):1433-1443.
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Two short implants versus one short implant with a cantilever: 5-Year results of a randomized clinical trial. Journal of Clinical Periodontology, 48(11):1480-1490.
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Production time, effectiveness and costs of additive and subtractive computer-aided manufacturing (CAM) of implant prostheses: A systematic review. Clinical Oral Implants Research, 32 Suppl:289-302.
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Soft tissue management at implants: Summary and consensus statements of group 2. The 6th EAO Consensus Conference 2021. Clinical Oral Implants Research, 32 Suppl:174-180.
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Sinus Floor Elevation with Biphasic Calcium Phosphate or Deproteinized Bovine Bone Mineral: Clinical and Histomorphometric Outcomes of a Randomized Controlled Clinical Trial. International Journal of Oral & Maxillofacial Implants, 35(5):1005-1012.
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Resin-Bonded Fixed Dental Prostheses with Zirconia Ceramic Single Retainers Show High Survival Rates and Minimal Tissue Changes After a Mean of 10 Years of Service. International Journal of Prosthodontics, 33(5):503-512.
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Implants sites with concomitant bone regeneration using a resorbable or non-resorbable membrane result in stable marginal bone levels and similar profilometric outcomes over 5 years. Clinical Oral Implants Research, 32(8):893-904.
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Core Ossification of Bone Morphogenetic Protein-2-Loaded Collagenated Bone Mineral in the Sinus. Tissue Engineering. Part A, 27(13-14):905-913.
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Short communication: Cemented implant reconstructions are associated with less marginal bone loss than screw-retained reconstructions at 3 and 5 years of loading. Clinical Oral Implants Research, 32(5):651-656.
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Augmentation of soft tissue volume at pontic sites: a comparison between a cross-linked and a non-cross-linked collagen matrix. Clinical Oral Investigations, 25(3):1535-1545.
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Zirconia reconstructions cemented on non-original titanium bases may result in increased bleeding on probing, probing depth values and varying mean marginal bone levels. International Journal of Prosthodontics, 34(5):560–566.
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Contour changes of peri-implant tissues are minimal and similar for a one- and a two-piece implant system over 12 years. Clinical Oral Investigations, 25(2):719-727.
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Immediate versus delayed application of bone morphogenetic protein-2 solution in damaged extraction sockets: a preclinical in vivo investigation. Clinical Oral Investigations, 25(1):275-282.
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Dimensional changes of the maxillary sinus augmented with a collagenated synthetic bone block or synthetic bone particulates: A pre-clinical study in rabbits. Journal of Clinical Periodontology, 47(11):1416-1426.
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Local tissue effects of various barrier membranes in a rat subcutaneous model. Journal of Periodontal & Implant Science, 50(5):327-339.
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Perceptibility and Acceptability of Color Differences of Single-Tooth Implants at the Restoration and Mucosa Levels: An Exploratory Clinical Study. International Journal of Prosthodontics, 33(5):487-492.
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The positive effect of tenting screws for primary horizontal guided bone regeneration: A retrospective study based on cone‐beam computed tomography data. Clinical Oral Implants Research, 31(9):846-855.
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Long‐term clinical and radiographic results after treatment or no treatment of small buccal bone dehiscences at posterior dental implants: A randomized, controlled clinical trial. Clinical Oral Implants Research, 31(6):517-525.
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Volume stability of the augmented sinus using a collagenated bovine bone mineral grafted in case of a perforated Schneiderian membrane: An experimental study in rabbits. Journal of Clinical Periodontology, 47(5):649-656.
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Randomized controlled clinical trial comparing implant sites augmented with a volume-stable collagen matrix or an autogenous connective tissue graft: 3-year data after insertion of reconstructions. Journal of Clinical Periodontology, 47(5):630-639.
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Lateral onlay grafting using different combinations of soft‐type synthetic block grafts and resorbable collagen membranes: An experimental in vivo study. Clinical Oral Implants Research, 31(4):303-314.
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Deproteinized bovine bone mineral is non-inferior to deproteinized bovine bone mineral with 10% collagen in maintaining the soft tissue contour post-extraction: A randomised trial. Clinical Oral Implants Research, 31(3):294-301.
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Late implant placement following ridge preservation versus early implant placement: A pilot randomized clinical trial for periodontally compromised non-molar extraction sites. Journal of Clinical Periodontology, 47(2):247-256.
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Augmentation of keratinized tissue at tooth and implant sites by using autogenous grafts and collagen-based soft-tissue substitutes. Journal of Clinical Periodontology, 47(1):64-71.
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Prospective randomized controlled clinical study comparing two types of two-piece dental implants supporting fixed reconstructions-Results at 5 years of loading. Clinical Oral Implants Research, 30(11):1126-1133.
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Randomized clinical study using xenograft blocks loaded with bone morphogenetic protein‐2 or autogenous bone blocks for ridge augmentation – a three‐dimensional analysis. Clinical Oral Implants Research, 30(9):872-881.
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Histologic analyses of flapless ridge preservation in sockets with buccal dehiscence defects using two alloplastic bone graft substitutes. Clinical Oral Investigations, 23(9):3589-3599.
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Veneered zirconia abutments cemented on non‐original titanium bases: 1‐year results of a prospective case series. Clinical Oral Implants Research, 30(8):735-744.
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Cemented vs screw-retained zirconia-based single implant reconstructions: A 3-year prospective randomized controlled clinical trial. Clinical Implant Dentistry and Related Research, 21(4):578-585.
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Tissue integration of zirconia and titanium implants with and without buccal dehiscence defects-A histologic and radiographic preclinical study. Clinical Oral Implants Research, 30(7):660-669.
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Efficacy of lateral bone augmentation performed simultaneously with dental implant placement. A systematic review and meta-analysis. Journal of Clinical Periodontology, 46:257-276.
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The effects of hard and soft tissue grafting and individualization of healing abutments at immediate implants: an experimental study in dogs. Journal of Periodontal & Implant Science, 49(3):171-184.
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Increasing the tissue thickness at implant sites using guided bone regeneration and an additional collagen matrix: Histologic observations in beagle dogs. Journal of Biomedical Materials Research. Part B, 107(3):741-749.
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The amount of keratinized mucosa may not influence peri-implant health in compliant patients: A retrospective 5-year analysis. Journal of Clinical Periodontology, 46(3):354-362.
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Comparison between two bone substitutes for alveolar ridge preservation after tooth extraction: Cone-beam computed tomography results of a non-inferiority randomized controlled trial. Journal of Clinical Periodontology, 46(3):373-381.
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Clinical and patient-reported outcomes of implants placed in autogenous bone grafts and implants placed in native bone: A case-control study with a follow-up of 5-16 years. Clinical Oral Implants Research, 30(3):242-251.
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Influence of wound closure on volume stability with the application of different GBR materials: an cone-beam computed tomographic study. Journal of Periodontal & Implant Science, 49(1):14-24.
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Randomized Controlled Clinical Trial of All-Ceramic Single-Tooth Implant Reconstructions Using Modified Zirconia Abutments: Results at 5 Years After Loading. International Journal of Periodontics and Restorative Dentistry, 39(1):17-27.
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Soft tissue substitutes to increase gingival thickness: Histologic and volumetric analyses in dogs. Journal of Clinical Periodontology, 46(1):96-104.
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Healing kinetics of oral soft tissue wounds treated with recombinant epidermal growth factor: Translation from a canine model. Journal of Clinical Periodontology, 46(1):105-117.
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Das Keramikimplantat Ein Update zum weissen Zahnimplantat. Implantologie, 27(2):165-170.
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Randomized Controlled Clinical Trial Comparing Cemented Versus Screw-Retained Single Crowns on Customized Zirconia Abutments: 3-Year Results. International Journal of Prosthodontics, 32(2):174-176.
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Randomized controlled clinical study of veneered zirconia abutments for single implant crowns: Clinical, histological, and microbiological outcomes. Clinical Implant Dentistry and Related Research, 20(6):988-996.
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Is the use of digital technologies for the fabrication of implant-supported reconstructions more efficient and/or more effective than conventional techniques: A systematic Review. Clinical Oral Implants Research, 29 Suppl:184-195.
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Early histological, microbiological, radiological, and clinical response to cemented and screw-retained all-ceramic single crowns. Clinical Oral Implants Research, 29(10):996-1006.
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Precision of digital implant models compared to conventional implant models for posterior single implant crowns: A within-subject comparison. Clinical Oral Implants Research, 29(9):931-936.
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10-year randomized trial (RCT) of zirconia-ceramic and metal-ceramic fixed dental prostheses. Journal of Dentistry, 76:32-39.
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Profilometric changes of peri-implant tissues over 5 years: A randomized controlled trial comparing a one- and two-piece implant system. Clinical Oral Implants Research, 29(8):864-872.
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Bone Regeneration of Peri-Implant Defects Using a Collagen Membrane as a Carrier for Recombinant Human Bone Morphogenetic Protein-2. BioMed Research International, 2018:5437361.
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Guidelines for development of Implant Dentistry in the next 10 years regarding innovation, education, certification, and associations. Clinical Oral Implants Research, 29(6):568-575.
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Alveolar ridge preservation in the esthetic zone. Periodontology 2000, 77(1):165-175.
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Tissue integration of zirconia and titanium implants with and without buccal dehiscence defects. Journal of Periodontal & Implant Science, 48(3):182-192.
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Randomized controlled clinical study assessing two membranes for guided bone regeneration of peri-implant bone defects: 3-year results. Clinical Oral Implants Research, 29(5):499-507.
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Non-interventional 1-year follow-up study of peri-implant soft tissues following previous soft tissue augmentation and crown insertion in single-tooth gaps. Journal of Clinical Periodontology, 45(4):504-512.
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Volumetric changes following ridge preservation or spontaneous healing and early implant placement with simultaneous guided bone regeneration. Journal of Clinical Periodontology, 45(4):484-494.
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Fracture strength of zirconia implant abutments on narrow diameter implants with internal and external implant abutment connections: A study on the titanium resin base concept. Clinical Oral Implants Research, 29(4):411-423.
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Osteogenic efficacy of BMP-2 mixed with hydrogel and bone substitute in peri-implant dehiscence defects in dogs: 16 weeks of healing. Clinical Oral Implants Research, 29(3):300-308.
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Effects of soft tissue augmentation procedures on peri-implant health or disease: A systematic review and meta-analysis. Clinical Oral Implants Research, (29 Suppl):32-49.
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Report of a human autopsy case in maxillary sinuses augmented using a synthetic bone substitute: Micro-computed tomographic and histologic observations. Clinical Oral Implants Research, 29(3):339-345.
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Randomized, controlled clinical two-centre study using xenogeneic block grafts loaded with recombinant human bone morphogenetic protein-2 or autogenous bone blocks for lateral ridge augmentation. Journal of Clinical Periodontology, 45(2):265-276.
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Effect of Hypoxia-Inducible Factor 1 on Early Healing in Extraction Sockets. BioMed Research International, 2018:8210637.
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Color Differences Between Pink Veneering Ceramics and the Human Gingiva. International Journal of Periodontics and Restorative Dentistry, 38(Suppl):s59-s65.
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Single-Tooth Replacement Using Dental Implants Supporting All-Ceramic and Metal-Based Reconstructions: Results at 18 Months of Loading. International Journal of Periodontics and Restorative Dentistry, 38(2):173-179.
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Effect of flapless ridge preservation with two different alloplastic materials in sockets with buccal dehiscence defects-volumetric and linear changes. Clinical Oral Investigations, 22(6):2187-2197.
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Clinical and histologic evaluation of different approaches to gain keratinized tissue prior to implant placement in fully edentulous patients. Clinical Oral Investigations, 22(5):2111-2119.
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Volumetric and linear changes at dental implants following grafting with volume-stable three-dimensional collagen matrices or autogenous connective tissue grafts: 6-month data. Clinical Oral Investigations, 22(3):1185-1195.
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Sinus floor elevation using implants coated with recombinant human bone morphogenetic protein-2: micro-computed tomographic and histomorphometric analyses. Clinical Oral Investigations, 22(2):829-837.
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Spectrophotometric analysis of fluorescent zirconia abutments compared to "conventional" zirconia abutments: A within subject controlled clinical trial. Clinical Implant Dentistry and Related Research, 19(4):760-766.
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Guided bone regeneration at zirconia and titanium dental implants: a pilot histological investigation. Clinical Oral Implants Research, 28(12):1592-1599.
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Randomized controlled clinical trial comparing one-piece and two-piece dental implants supporting fixed and removable dental prostheses: 4- to 6-year observations. Clinical Oral Implants Research, 28(12):1553-1559.
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The influence of the emergence profile on the amount of undetected cement excess after delivery of cement-retained implant reconstructions. Clinical Oral Implants Research, 28(12):1515-1522.
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Guided bone regeneration with particulate vs. block xenogenic bone substitutes: a pilot cone beam computed tomographic investigation. Clinical Oral Implants Research, 28(11):e262-e270.
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Randomized controlled clinical pilot study of all-ceramic single-tooth implant reconstructions: clinical and microbiological outcomes at one year of loading. Clinical Oral Implants Research, 28(4):406-413.
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Volumetric changes and peri-implant health at implant sites with or without soft tissue grafting in the esthetic zone, a retrospective case-control study with a 5-year follow-up. Clinical Oral Implants Research, 28(11):1459-1465.
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Effect of ridge preservation for early implant placement - is there a need to remove the biomaterial?. Journal of Clinical Periodontology, 44(5):556-565.
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A systematic review of the survival and complication rates of resin-bonded fixed dental prostheses after a mean observation period of at least 5 years. Clinical Oral Implants Research, 28(11):1421-1432.
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Recombinant bone morphogenetic protein-2 and platelet-derived growth factor-BB for localized bone regeneration. Histologic and radiographic outcomes of a rabbit study. Clinical Oral Implants Research, 28(11):e236-e243.
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Auf feuerfesten Stümpfen gesinterte keramische Veneers : Plädoyer für ein manuelles Vorgehen. Quintessenz Zahntechnik:166-177.
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Esthetic assessments in implant dentistry: objective and subjective criteria for clinicians and patients. Periodontology 2000, 73(1):193-202.
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Biodegradation and tissue integration of various polyethylene glycol matrices: a comparative study in rabbits. Clinical Oral Implants Research, 28(11):e244-e251.
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Comparison of Fixed Dental Prostheses with Zirconia and Metal Frameworks: Five-Year Results of a Randomized Controlled Clinical Trial. International Journal of Prosthodontics, 30(5):426-428.
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Treatment concepts for the posterior maxilla and mandible: short implants versus long implants in augmented bone. Journal of Periodontal & Implant Science, 47(1):2.
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Short dental implants (6 mm) versus long dental implants (11-15 mm) in combination with sinus floor elevation procedures: 3-year results from a multicentre, randomized, controlled clinical trial. Journal of Clinical Periodontology, 44(4):438-445.
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Soft tissue volume augmentation at dental implant sites using a volume stable three-dimensional collagen matrix – histological outcomes of a preclinical study. Journal of Clinical Periodontology, 44(2):185-194.
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Localized bone regeneration around dental implants using recombinant bone morphogenetic protein-2 and platelet-derived growth factor-BB in the canine. Clinical Oral Implants Research, 28(11):1334-1341.
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Volumetric changes at pontic sites with or without soft tissue grafting. A controlled clinical study with a 10-year follow-up. Journal of Clinical Periodontology, 44(2):178-184.
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Randomized clinical study assessing two membranes for guided bone regeneration of peri-implant bone defects: clinical and histological outcomes at 6 months. Clinical Oral Implants Research, 28(10):1309-1317.
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Discoloration of the mucosa caused by different restorative materials - a spectrophotometric in vitro study. Clinical Oral Implants Research, 28(9):1133-1138.
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Bone augmentation at peri-implant dehiscence defects comparing a synthetic polyethylene glycol hydrogel matrix vs. standard guided bone regeneration techniques. Clinical Oral Implants Research, 28(7):e76-e83.
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A randomized controlled clinical trial comparing small buccal dehiscence defects around dental implants treated with guided bone regeneration or left for spontaneous healing. Clinical Oral Implants Research, 28(3):348-354.
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Spectrophotometric and visual evaluation of peri-implant soft tissue color. Clinical Oral Implants Research, 28(2):192-200.
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Threshold Values for the Perception of Color Changes in Human Teeth. International Journal of Periodontics and Restorative Dentistry, 36(6):777-783.
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The Esthetic Effect of Veneered Zirconia Abutments for Single-Tooth Implant Reconstructions: A Randomized Controlled Clinical Trial. Clinical Implant Dentistry and Related Research, 18(6):1210-1217.
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Randomized controlled clinical study evaluating effectiveness and safety of a volume-stable collagen matrix compared to autogenous connective tissue grafts for soft tissue augmentation at implant sites. Journal of Clinical Periodontology, 43(10):874-885.
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Palatal wound healing using a xenogeneic collagen matrix - histological outcomes of a randomized controlled clinical trial. Journal of Clinical Periodontology, 43(12):1124-1131.
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Soft tissue stability and volumetric changes after 5 years in pontic sites with or without soft tissue grafting: a retrospective cohort study. Clinical Oral Implants Research, 27(8):969-974.
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Discoloration of the Peri-implant Mucosa Caused by Zirconia and Titanium Implants. International Journal of Periodontics and Restorative Dentistry, 36(1):39-45.
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Prospective randomized controlled clinical study comparing two types of two-piece dental implants supporting fixed reconstructions - results at 1 year of loading. Clinical Oral Implants Research, 27(9):1169-1177.
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Surface roughness of dental implants and treatment time using six different implantoplasty procedures. Clinical Oral Implants Research, 27(7):776-781.
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Guided bone regeneration of peri-implant defects with particulated and block xenogenic bone substitutes. Clinical Oral Implants Research, 27(5):567-576.
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Randomized Controlled Clinical Trial of All-Ceramic Single Tooth Implant Reconstructions Using Modified Zirconia Abutments: Radiographic and Prosthetic Results at 1 Year of Loading. Clinical Implant Dentistry and Related Research, 18(3):462-472.
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Marginal bone-level alterations of loaded zirconia and titanium dental implants: an experimental study in the dog mandible. Clinical Oral Implants Research, 27(4):412-420.
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Prospective randomized controlled clinical study comparing two dental implant types: volumetric soft tissue changes at 1 year of loading. Clinical Oral Implants Research, 27(4):406-411.
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Histological analysis of loaded zirconia and titanium dental implants: an experimental study in the dog mandible. Journal of Clinical Periodontology, 42(10):967-975.
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Therapeutic concepts and methods for improving dental implant outcomes. Summary and consensus statements. The 4th EAO Consensus Conference 2015. Clinical Oral Implants Research, 26 Suppl:202-206.
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EAO Supplement Working Group 4 - EAO CC 2015 Short implants versus sinus lifting with longer implants to restore the posterior maxilla: a systematic review. Clinical Oral Implants Research, 26 Suppl:154-169.
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The efficacy of BMP-2 preloaded on bone substitute or hydrogel for bone regeneration at peri-implant defects in dogs. Clinical Oral Implants Research, 26(12):1456-1465.
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Effect of platelet-derived growth factor-BB on tissue integration of cross-linked and non-cross-linked collagen matrices in a rat ectopic model. Clinical Oral Implants Research, 26(3):263-270.
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Critical soft-tissue dimensions with dental implants and treatment concepts. Periodontology 2000, 66(1):106-118.
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Threshold value for the perception of color changes of human gingiva. International Journal of Periodontics and Restorative Dentistry, 34(6):757-762.
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Clinical efficacy of periodontal plastic surgery procedures: Consensus report of Group 2 of the 10th European Workshop on Periodontology. Journal of Clinical Periodontology, 41 Suppl:36-43.
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Maxillary anterior ridge augmentation with recombinant human bone morphogenetic protein 2. International Journal of Periodontics and Restorative Dentistry, 34(4):551-557.
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Efficacy of soft tissue augmentation around dental implants and in partially edentulous areas: a systematic review. Journal of Clinical Periodontology, 41(S15):S77-S91.
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All-ceramic single-tooth implant reconstructions using modified zirconia abutments: a prospective randomized controlled clinical trial of the effect of pink veneering ceramic on the esthetic outcomes. International Journal of Periodontics and Restorative Dentistry, 34(1):29-37.
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Prospective randomized controlled clinical study comparing two dental implant systems: demographic and radiographic results at one year of loading. Clinical Oral Implants Research, 25(2):142-149.
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Biodegradation and bone formation of various polyethylene glycol hydrogels in acute and chronic sites in mini-pigs. Clinical Oral Implants Research, 25(4):511-521.
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Radiographic evaluation of different techniques for ridge preservation after tooth extraction: a randomized controlled clinical trial. Journal of Clinical Periodontology, 40(1):90-98.
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Impact of recombinant platelet-derived growth factor BB on bone regeneration: a study in rabbits. International Journal of Periodontics and Restorative Dentistry, 32(2):195-202.
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Soft tissue regeneration using collagen-based matrices : experimental and clinical studies. 2012, University of Zurich, Medizinische Fakultät.
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Systematic review of pre-clinical models assessing implant integration in locally compromised sites and/or systemically compromised animals. Journal of Clinical Periodontology, 39 Suppl:37-62.
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Evaluation of a biodegradable synthetic hydrogel used as a guided bone regeneration membrane: an experimental study in dogs. Clinical Oral Implants Research, 23(2):160-168.
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Tissue integration of collagen-based matrices: an experimental study in mice. Clinical Oral Implants Research, 23(12):1333-1339.
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Impact of a collagen matrix on early healing, aesthetics and patient morbidity in oral mucosal wounds - a randomized study in humans. Journal of Clinical Periodontology, 39(2):157-165.
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Angiogenic activity of an enamel matrix derivative (EMD) and EMD-derived proteins: an experimental study in mice. Journal of Clinical Periodontology, 38(3):253-260.
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Biodegradation, soft and hard tissue integration of various polyethylene glycol hydrogels: a histomorphometric study in rabbits. Clinical Oral Implants Research, 22(11):1247-1254.
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Tissue integration of a new titanium-zirconium dental implant: a comparative histologic and radiographic study in the canine. Journal of Periodontology, 82(10):1453-1461.
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Soft tissue volume augmentation by the use of collagen-based matrices in the dog mandible – a histological analysis. Journal of Clinical Periodontology, 38(11):1063-1070.
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Local tolerance and efficiency of two prototype collagen matrices to increase the width of keratinized tissue. Journal of Clinical Periodontology, 38(2):173-179.
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Ridge augmentation using recombinant bone morphogenetic protein-2 techniques: an experimental study in the canine. Journal of Periodontology, 81(12):1829-1838.
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Evaluation of parathyroid hormone bound to a synthetic matrix for guided bone regeneration around dental implants: a histomorphometric study in dogs. Journal of Periodontology, 81(5):737-747.
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Soft tissue volume augmentation by the use of collagen-based matrices: a volumetric analysis. Journal of Clinical Periodontology, 37(7):659-666.
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Unlocking the mystery of periodontal regeneration - different tissues, different phenotypes. Journal de Parodontologie et d'Implantologie Orale, 29(1):23-60.
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A bioreactor test system to mimic the biological and mechanical environment of oral soft tissues and to evaluate substitutes for connective tissue grafts. Biotechnology and Bioengineering, 107(6):1029-1039.
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A systematic review assessing soft tissue augmentation techniques. Clinical Oral Implants Research, 20(Suppl.):146-165.
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Evaluation of a new biodegradable membrane to prevent gingival ingrowth into mandibular bone defects in minipigs. Clinical Oral Implants Research, 20(1):7-16.
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A randomized, controlled clinical trial to evaluate a new membrane for guided bone regeneration around dental implants. Clinical Oral Implants Research, 20(2):162-168.
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Assessment of the potential of growth factors for localized alveolar ridge augmentation: a systematic review. Journal of Clinical Periodontology, 35(8 Supp):255-281.
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Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite/tricalciumphosphate. Clinical Oral Implants Research, 19(2):188-195.